TTEC was founded in 2010 as a joint venture between the Wilmer Eye Institute and the Johns Hopkins University Department of Biomedical Engineering to establish a focus in research, education, and industrial development in the field of regenerative medicine.
THE MISSION OF THE JOHNS HOPKINS TRANSLATIONAL TISSUE ENGINEERING CENTER (TTEC) IS TO BLAZE NEW TRAILS IN THE FIELDS OF TISSUE ENGINEERING AND IMMUNOENGINEERING WHILE TRAINING TOMORROW’S TOP RESEARCHERS AND ACCELERATING THE DELIVERY OF REGENERATIVE MEDICINE TECHNOLOGIES TO PATIENTS.
TTEC comprises nine core faculty members who span five departments—both clinical and basic science—across The Johns Hopkins University and the School of Medicine. We are home to roughly 130 trainees from undergraduate students to postdoctoral and clinical fellows. We are located on the fifth floor of the state-of-the-art Smith Building on the School of Medicine’s East Baltimore campus. The laboratories are designed in an open floor plan to enhance interdisciplinary research.
There are three prongs to our work: research, education and translation.
Building on the excellence of Johns Hopkins’ clinical and engineering environments, TTEC research programs revolve around fundamental materials science, engineering, and biology along with a spectrum of enabling technologies for advancing regenerative medicine translation in nearly every clinical field.
Collaborating Clinical Departments, Centers and Institutes
- NEUROLOGY AND NEUROSURGERY
- ORTHOPAEDIC SURGERY
- PLASTIC AND RECONSTRUCTIVE SURGERY
- RADIOLOGY AND RADIOLOGICAL SCIENCE
- BLOOMBERG~KIMMEL INSTITUTE FOR CANCER IMMUNOTHERAPY
- INSTITUTE FOR CELL ENGINEERING
- INSTITUTE FOR COMPUTATIONAL MEDICINE
- INSTITUTE FOR NANOBIOTECHNOLOGY
- KENNEDY KRIEGER INSTITUTE
- SIDNEY KIMMEL COMPREHENSIVE CANCER CENTER
By discovering basic biological principles, engineering innovations and implementing our findings in the clinic, we strive to significantly improve the health of patients suffering from an array of maladies, including trauma, cancer and immune disorders. See our Research Page to learn more about our strategy.
Our research projects generally fall within the categories of tissue engineering and immunoengineering. Visit our Core Faculty Page to find out about ongoing projects.
The TTEC faculty works hard to train the next generation of researchers in regenerative medicine by teaching undergraduate and graduate students and mentoring student researchers and postdoctoral fellows. TTEC faculty members also lead two focus areas for undergraduate and graduate students that are part of the #1 ranked Biomedical Engineering Program. By teaching across multiple educational programs, departments, schools and campuses, we help foster the cross-pollination of ideas and interdisciplinary collaboration. Please visit our Education Page to learn more.
Our research and innovation does not reach its fulfillment until it has been applied in the clinic and shown to improve patient health. As a result of this commitment, we participate in many clinical trials and industry collaborations, and several startup companies have been formed from our group. Please contact Bahar Zarrabi if you are interested in discussing a new collaboration.
Ongoing Clinical Trials
- Assessment of Primary Oxygenation and Airflow Measurement for Endoscopic Laryngeal Surgery (NCT03222869)
- Treatment Alternatives in Idiopathic subglottic stenosis (iSGS) (NCT02481817)
- Safety Study of Acellular Adipose Tissue for Soft Tissue Reconstruction (NCT02817984)
- Acellular Adipose Tissue for Soft Tissue Reconstruction (NCT03544632)
- A Safety and Tolerability Study of UBX0101 in Patients with Osteoarthritis of the Knee (NCT03513016)