The main themes of research in my laboratory are angiogenesis, immuno-oncology, Quantitative Systems Pharmacology (QSP), and development of oncolytic, anti-angiogenic and immuno-activating peptides for therapeutic applications. We conduct both computational and experimental studies. Our QSP studies use spatial transcriptomics of tumors and build cohorts of virtual patients and digital twins to conduct virtual clinical trials and identify biomarkers.
