Bioelectronic devices are important as fundamental research tools for probing and understanding the brain with high spatiotemporal resolution, and as potential therapeutic avenues for treating brain diseases, disorders, and injuries. The Yang Lab aims to develop novel bioelectronics and biomaterials for brain-machine interfaces, regenerative medicine, and the study of human neural development and diseases. We drew inspiration from biological systems and art forms to design and develop a series of bio-inspired and art-inspired bioelectronics. Our studies encompass neural probes for in vivo brain-machine interface, electronic scaffolds for brain repair, and platforms for detecting human genetic diseases and tracking human neural development using human brain organoids. Our research integrates with TTEC’s core themes, including tissue engineering, sensing and imaging, advanced biomanufacturing, and disease modeling.